From Florence: Motorway A11 (Firenze-Pisa) and go out to Altopascio. Follow the indications for Bientina.
From La Spezia: Motorway A12 and go out to Pisa Centro. Take the speedway Fi-Pi-Li, exit: Pontedera, follow Lucca. After Bientina, turn left to Buti.
From Cascine di Buti you will find several directions indicating "Affittacamere San Francesco".